PT-141 (10mg)

Description

Product: PT-141 (10mg) Product Overview: PT-141, also known as Bremelanotide, is a synthetic cyclic heptapeptide derived from alpha-MSH (melanocyte-stimulating hormone). It features a lactam bridge that contributes to its cyclic conformation and has been studied for its potential to enhance binding affinity to melanocortin receptors. PT-141 has been investigated in preclinical research for its interactions with specific receptors and pathways associated with central and peripheral systems. Research Profile: Research into PT-141 focuses on its potential involvement in melanocortin receptor activity and associated biological processes. Laboratory studies examine its interaction with cellular signaling pathways and receptor-binding dynamics. - Melanocortin Receptors: PT-141 has been studied for its binding to MC3R and MC4R, with research investigating its role in receptor signaling and downstream intracellular processes. - Neural Pathways: Preclinical studies explore its potential effects on central nervous system pathways, particularly those involving the hypothalamus and its regulatory mechanisms. - Vasoactive Properties: PT-141 has been evaluated in research models for its potential effects on vasodilation and vascular tone, potentially mediated through receptor-specific interactions. - Hormonal Regulation: Research investigates its influence on alpha-MSH activity and downstream melanocortin receptor pathways that may affect hormonal signaling. - Cyclic Peptide Stability: The lactam bridge has been studied for its role in enhancing conformational stability, receptor affinity, and peptide longevity in laboratory settings. Key Research Applications: PT-141 has been widely investigated in preclinical models for its receptor-specific activity and influence on biological systems. - Melanocortin System Investigations: Studied for its ability to bind and potentially activate MC3R and MC4R, contributing to research on melanocortin system dynamics. - Central Nervous System Studies: Utilized in preclinical models examining hypothalamic pathways and their regulatory effects on physiological responses. - Vascular Research Models: Investigated for its potential role in modulating vascular tone and exploring mechanisms of vasodilation. - Hormonal Pathway Analysis: Deployed in research models studying alpha-MSH activity and related melanocortin receptor pathways. Specifications: Peptide Content: 10mg per vial Appearance: Lyophilized powder Storage & Handling: Store in a cool, dry environment protected from light and moisture. Reconstitution and handling should be performed using standard laboratory procedures and appropriate laboratory controls.